发明名称 TREATMENT OF CANCERS HAVING RESISTANCE TO CHEMOTHERAPEUTIC AGENTS
摘要 <p>The present invention provides compositions and uses thereof for treating cancer with DAST, 4 {4- [3- (4-chloro-3-trif luoromethyl phenyl) -ureido] - 3 -fluorophenoxy} -pyridine-2-carboxylic acid methylamide of the formula I, including all polymorphs, hydrates, pharmaceutically acceptable salts, metab olites, prodrugs, solvates or combinations thereof. Any cancer can be treate d, including cancers that have acquired resistance to another therapeutic ag ent, such as kinase inhibitors. DAST can also be used to treat cancers which have become refractory to other chemotherapeutic agents.</p>
申请公布号 CA2675979(A1) 申请公布日期 2008.07.24
申请号 CA20082675979 申请日期 2008.01.18
申请人 BAYER HEALTHCARE LLC 发明人 GEDRICH, RICHARD W.;WILHELM, SCOTT
分类号 A61K31/44;A61K31/506;A61K31/517;A61K31/5377;A61K45/06;A61P35/00;A61P35/02;A61P35/04 主分类号 A61K31/44
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