摘要 |
<p>The present invention provides compositions and uses thereof for treating cancer with DAST, 4 {4- [3- (4-chloro-3-trif luoromethyl phenyl) -ureido] - 3 -fluorophenoxy} -pyridine-2-carboxylic acid methylamide of the formula I, including all polymorphs, hydrates, pharmaceutically acceptable salts, metab olites, prodrugs, solvates or combinations thereof. Any cancer can be treate d, including cancers that have acquired resistance to another therapeutic ag ent, such as kinase inhibitors. DAST can also be used to treat cancers which have become refractory to other chemotherapeutic agents.</p> |