发明名称 |
USE OF I) A POLYGLYCOL AND II) AN ACTIVE DRUG SUBSTANCE FOR THE PREPARATION OF A PHARMACEUTICAL COMPOSITION FOR I)MITIGATING THE RISK OF ALCOHOL INDUCED DOSE DUMPING AND/OR II) REDUCING THE RISK OF DRUG ABUSE |
摘要 |
Abuse resistant polyglycol-based pharmaceutical compositions are disclosed. The composition contains one or more polyglycols and one or more active substances and it is resistant to crushing, melting and/or extraction. Moreover, such compositions have the same or lower solubility in ethanolic-aqueous medium, i.e. they are not subject to ethanol-induced dose dumping effect. |
申请公布号 |
CA2930487(A1) |
申请公布日期 |
2008.07.24 |
申请号 |
CA20082930487 |
申请日期 |
2008.01.16 |
申请人 |
EGALET LTD. |
发明人 |
DOWNIE, KEN;PEDERSEN, ANDERS VAGNE;HAAHR, ANNE-METTE;HEMMINGSEN, PERNILLE HEYRUP;BAR-SHALOM, DANIEL |
分类号 |
A61K47/34;A61K9/00 |
主分类号 |
A61K47/34 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|