发明名称 USE OF KYNURENIC ACID AND DERIVATIVES THEREOF IN THE TREATMENT OF CONDITIONS OF THE GASTROINTESTINAL TRACT ACCOMPANIED BY HYPERMOTILITY AND INFLAMMATION OR GOUT OR MULTIPLE SCLEROSIS
摘要 The subject of the invention is the use of kynurenic acid (KYNA) and its derivatives and physiologically acceptable salts of the general formula (I) in the manufacture of a medicament for the treatment of conditions characterized by pathophysiological conditions of the GI tract accompanied by increased motility and an elevated activity of the enzyme xanthine oxidoreductase (XOR), and further for the treatment of gout or multiple sclerosis. The meanings of the substituents of general formula (I) are defined in the claims.
申请公布号 WO2008087461(A2) 申请公布日期 2008.07.24
申请号 WO2008HU00005 申请日期 2008.01.15
申请人 SZEGEDI TUDOMANYEGYETEM;VECSEI, LASZLO;BOROS, MIHALY;KASZAKI, JOZSEF;FUELOEP, FERENC;TOLDI, JOZSEF;SZATMARI, ISTVAN 发明人 VECSEI, LASZLO;BOROS, MIHALY;KASZAKI, JOZSEF;FUELOEP, FERENC;TOLDI, JOZSEF;SZATMARI, ISTVAN
分类号 A61K31/47;A61P1/00;A61P19/06;A61P25/28 主分类号 A61K31/47
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