USE OF KYNURENIC ACID AND DERIVATIVES THEREOF IN THE TREATMENT OF CONDITIONS OF THE GASTROINTESTINAL TRACT ACCOMPANIED BY HYPERMOTILITY AND INFLAMMATION OR GOUT OR MULTIPLE SCLEROSIS
摘要
The subject of the invention is the use of kynurenic acid (KYNA) and its derivatives and physiologically acceptable salts of the general formula (I) in the manufacture of a medicament for the treatment of conditions characterized by pathophysiological conditions of the GI tract accompanied by increased motility and an elevated activity of the enzyme xanthine oxidoreductase (XOR), and further for the treatment of gout or multiple sclerosis. The meanings of the substituents of general formula (I) are defined in the claims.
申请公布号
WO2008087461(A2)
申请公布日期
2008.07.24
申请号
WO2008HU00005
申请日期
2008.01.15
申请人
SZEGEDI TUDOMANYEGYETEM;VECSEI, LASZLO;BOROS, MIHALY;KASZAKI, JOZSEF;FUELOEP, FERENC;TOLDI, JOZSEF;SZATMARI, ISTVAN