发明名称 |
HIGH MOLECULAR- TITANIA-HYDROXYAPATITE COMPOSITE NANOFIBERS AND ITS MANUFACTURING METHOD AND, TITANIA-HYDROXYAPATITE COMPOSITE NANOFIBERS AND ITS MANUFACTURING METHOD |
摘要 |
A titania-hydroxyapatite composite nanofiber is provided to expand applicabilities as a bone substituting material, and to improve biocompatibility and bio-friendliness. A preparation of titania-hydroxyapatite composite nanofiber comprises the steps of: dissolving a polyvinyl group polymer in 2-methoxyethanol to obtain a 8-13wt% concentration polymer sol; mixing Titanium(IV) isopropoxide (TIP), 2-methoxyethanol, and acetic acid at the same volume ratio to obtain a ceramic precursor sol; mixing the polymer sol and the precursor sol at a ratio of 4-6:6-4 and stirring the mixture over a period of 10-14 hours to obtain a polymer ceramic precursor sol; adding the polymer ceramic precursor sol to a hydroxyapatite(HA) sol at a volume ratio of 4-6 and stirring the mixture over a period of 20-28 hours to obtain a polymer/titania/HA sol; electro-spinning the resulting sol to obtain the target nanofiber. Preferably, calcination is carried out at 600deg.C for 3 hours for titania and HA to have a ceramic crystalline structure. |
申请公布号 |
KR100848468(B1) |
申请公布日期 |
2008.07.24 |
申请号 |
KR20070037124 |
申请日期 |
2007.04.16 |
申请人 |
CHANG, KI WHAN;KANG, IN GYU;KIM, SUK YOUNG;BK-MEDENT CO., LTD. |
发明人 |
CHANG, KI WHAN;KANG, IN GYU;KIM, SUK YOUNG;KIM, HONG MI |
分类号 |
A61L27/40;A61L27/50;A61L27/56;A61L27/58 |
主分类号 |
A61L27/40 |
代理机构 |
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代理人 |
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主权项 |
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