POLYMORPHISMS IN THE EGFR PATHWAY AS MARKERS FOR CANCER TREATMENT
摘要
The invention provides compositions and methods for identifying patients for single agent anti-EGFR therapy. The methods comprise determining the genomic polymorphism present in a predetermined region of a gene of interest and correlating the polymorphism to the predictive response. Patients identified as responsive are then treated with the appropriate therapy.
申请公布号
WO2008088860(A2)
申请公布日期
2008.07.24
申请号
WO2008US00660
申请日期
2008.01.17
申请人
UNIVERSITY OF SOUTHERN CALIFORNIA;LENZ, HEINZ-JOSEF;ZHANG, WU