摘要 |
The present invention relates to novel subst ituted quinoline derivatives according to the general Formula (Ia) or Formula (Ib): including any stereochemically isomeric form thereof, a pharmaceutically acceptable salt thereof, a N-oxide form thereof or a solvate thereof. The claimed compounds are useful for the treatment of a bacterial infection. Also claimed is a composition comprising a pharmaceutically acceptable carrier and, as active ingredient, a therapeutically effective amount of the claimed compounds, the use of the claimed compounds or composit ions for the manufacture of a medicament for the treatment of a bacterial infection and a process for preparing the claimed compounds. |
申请人 |
JANSSEN PHARMACEUTICA N.V.;GUILLEMONT, JEROME, EMILE, GEORGES;DORANGE, ISMET;LANCOIS, DAVID, FRANCIS, ALAIN;VILLALGORDO-SOTO, JOSE, MANUEL;SIMONNET, YVAN, RENE, FERDINAND;MOTTE, MAGALI, MADELEINE, SIMONE;ANDRIES, KOENRAAD, JOZEF, LODEWIJK, MARCEL;KOUL, ANIL |
发明人 |
GUILLEMONT, JEROME, EMILE, GEORGES;DORANGE, ISMET;LANCOIS, DAVID, FRANCIS, ALAIN;VILLALGORDO-SOTO, JOSE, MANUEL;SIMONNET, YVAN, RENE, FERDINAND;MOTTE, MAGALI, MADELEINE, SIMONE;ANDRIES, KOENRAAD, JOZEF, LODEWIJK, MARCEL;KOUL, ANIL |