PREPARATION AND USE OF MAGNESIUM AMIDES

摘要

The present application relates to mixed Mg/Li amides of the general formula R<SUP>1</SUP>R<SUP>2</SUP>N-Mg-NR<SUP>3</SUP>R<SUP>4</SUP>.zLiY (II) wherein R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, and R<SUP>4</SUP> are, independently, selected from H, substituted or unsubstituted aryl or heteroaryl containing one or more heteroatoms, linear, branched or cyclic, substituted or unsubstituted alkyl, alkenyl, alkynyl, or silyl derivatives thereof; and R<SUP>1</SUP> and R<SUP>2</SUP> together, or R<SUP>3</SUP> and R<SUP>4</SUP> together can be part of a cyclic or polymeric structure; and wherein at least one of R<SUP>1</SUP> and R<SUP>2</SUP> and at least one of R<SUP>3</SUP> and R<SUP>4</SUP> is other than H; Y is selected from the group consisting of F; Cl; Br; I; CN; SCN; NCO; HaIO<SUB>n</SUB>, wherein n = 3 or 4 and Hal is selected from Ci, Br and I; NO<SUB>3</SUB>; BF<SUB>4</SUB>; PF<SUB>6</SUB>; H; a carboxylate of the general formula R<SUP>x</SUP>CO<SUB>2</SUB>; an alcoholate of the general formula OR<SUP>x</SUP>; a thiolate of the general formula SR<SUP>x</SUP>; R<SUP>x</SUP>P(O)O<SUB>2</SUB>; or SCOR<SUP>x</SUP>; or SCSR<SUP>x</SUP>; O<SUB>n</SUB>SR<SUP>x</SUP>, wherein n = 2 or 3; or NO<SUB>n</SUB>, wherein n = 2 or 3; and a derivative thereof; wherein R<SUP>x</SUP> is a substituted or unsubstituted aryl or heteroaryl containing one or more heteroatoms, linear, branched or cyclic, substituted or unsubstituted alkyl, alkenyl, alkynyl, or derivatives thereof, or H; m is O or 1; and z > 1; as well as a process for the preparation of the mixed Mg/Li amides and the use of these amides, e.g. as bases.