<p>A portable, self-contained air-purifying device that enables a person standing outside the device to use his hands to manipulate objects within the device so that those objects can be kept in particulate- free environment while being manipulated. The device includes a housing having a sealable opening, an airflow-generating device that circulates the air within the housing, an air filter, and manipulation structure configured to enable a person located outside said housing to use their hands to grasp and manipulate objects which have been placed within the chamber that has been subsequently sealed.</p>