| 发明名称 |
STEM CELL GENE TARGETING |
| 摘要 |
<p>The invention provides a method for generating a transgenic eukaryotic ce ll population having a modified human Rosa26 locus, which method includes in troducing a functional DNA sequence into the human Rosa26 locus of starting eukaryotic cells. Also provided are targeting vectors useful in the method, as well as a cell population and a transgenic non-human animal comprising a modified human Rosa26 locus. Finally, the invention provides an isolated DNA sequence corresponding to the human Rosa26 locus.</p> |
| 申请公布号 |
CA2675952(A1) |
申请公布日期 |
2008.07.24 |
| 申请号 |
CA20082675952 |
申请日期 |
2008.01.18 |
| 申请人 |
MOUNT SINAI SCHOOL OF MEDICINE OF THE CITY UNIVERSITY OF NEW YORK |
发明人 |
LUCHE, HERVE;IRION, STEFAN;KELLER, GORDON;FEHLING, HANS JOERG;GADUE, PAUL |
| 分类号 |
A01K67/027;C07H21/00;C12N5/0735;C12N5/10;C12N15/09;C12N15/85;C12N15/90 |
主分类号 |
A01K67/027 |
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