发明名称 COMBINATION CANCER THERAPY
摘要 The present invention relates to a method of treating cancer in a subject in need thereof, by administering to a subject in need thereof a first amount of an Aurora kinase inhibitor or a pharmaceutically acceptable salt or hydrate thereof, in a first treatment procedure, and a second amount of an anti-cancer agent in a second treatment procedure. The first and second amounts together comprise a therapeutically effective amount. The effect of the Aurora kinase inhibitor and the anti-cancer agent may be additive or synergistic.
申请公布号 WO2007136615(A3) 申请公布日期 2008.07.24
申请号 WO2007US11595 申请日期 2007.05.15
申请人 MERCK & CO., INC.;BANYU PHARMACEUTICAL CO., LTD.;VERTEX PHARMACEUTICALS INCORPORATED;BUSER-DOEPNER, CAROLYN, A.;BLOECHER, ANDREW, M.;FREEDMAN, STEVEN, J.;HARDING, MATTHEW, W.;HASAKO, SHINICHI;HOOVER, RUSSELL, R.;SHIMOMURA, TOSHIYASU 发明人 BLOECHER, ANDREW, M.;FREEDMAN, STEVEN, J.;HARDING, MATTHEW, W.;HASAKO, SHINICHI;HOOVER, RUSSELL, R.;SHIMOMURA, TOSHIYASU
分类号 A61K31/506 主分类号 A61K31/506
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