发明名称 Pharmaceutical compounds
摘要 Compounds or their salts of general formula (I): A-B-N(O)<SUB>s </SUB>wherein: s is an integer equal to 1 or 2; A=R-T<SUB>1</SUB>-, wherein R is the drug radical and T<SUB>1</SUB>=(CO)<SUB>t </SUB>or (X)<SUB>t'</SUB>, wherein X=O, S, NR<SUB>1c</SUB>, R<SUB>1c </SUB>is H or a linear or branched alkyl or a free valence, t and t' are integers and equal to zero or 1, with the proviso that t=1 when t'=0; t=0 when t'=1; B=-T<SUB>B</SUB>-X<SUB>2</SUB>-O- wherein T<SUB>B</SUB>=(CO) when t=0, T<SUB>B</SUB>=X when t'=0, X being as above defined; X<SUB>2 </SUB>is equal to R<SUB>1B-X-R</SUB><SUB>2B </SUB>radical wherein X is as above defined, R<SUB>1B </SUB>and R<SUB>2B</SUB>, equal to or different from each other, are linear or branched C<SUB>1</SUB>-C<SUB>6 </SUB>alkylenes, or X<SUB>2 </SUB>is a radical wherein two alkylene chains C<SUB>1</SUB>-C<SUB>4 </SUB>are linked to nonadjacent positions of a central ring having 4 or 6 atoms, said ring being an unsaturated cycloaliphatic ring, or a saturated or aromatic heterocylic ring, containing one or two heteroatoms, equal or different, selected from O, S, N; wherein the unsaturated cycloaliphatic ring does not have aromatic character according to Huckel's rule.
申请公布号 US7399878(B2) 申请公布日期 2008.07.15
申请号 US20060642783 申请日期 2006.12.21
申请人 NICOX S.A. 发明人 DEL SOLDATO PIERO
分类号 C07C203/00;C07D499/48;A61K31/21;A61K31/221;A61K31/222;A61K31/235;A61K31/365;A61K31/366;A61K31/43;A61K31/4365;A61K31/437;A61K31/454;A61K31/473;A61K31/496;A61K31/663;A61K31/704;A61K38/00;A61P1/02;A61P3/06;A61P3/10;A61P7/02;A61P9/08;A61P9/12;A61P11/06;A61P11/08;A61P11/10;A61P11/12;A61P19/08;A61P25/02;A61P25/28;A61P29/00;A61P31/04;A61P31/12;A61P35/00;A61P37/08;A61P43/00;C07C69/618;C07C69/708;C07C203/04;C07C219/10;C07C219/14;C07C219/22;C07C219/24;C07C219/30;C07C229/42;C07C233/25;C07C317/44;C07D219/10;C07D295/08;C07D295/088;C07D307/80;C07D309/30;C07D401/12;C07D471/04;C07D495/04;C07D499/00;C07D499/68;C07F9/38;C07H15/252 主分类号 C07C203/00
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