| 摘要 |
This invention relates to compounds which are N-oxides and derivatives thereof, as well as their use to treat HIF related diseases. These compounds have the general formula set out below and are used to treat a variety of diseases associated with HIF: wherein R is an alkyl, aryl, arakyl or derivatives thereof such as CH<SUB>3</SUB>OCH<SUB>2</SUB>CH<SUB>2</SUB>-, CH<SUB>3</SUB>CH<SUB>2</SUB>OCH<SUB>2</SUB>CH<SUB>2</SUB>-, C<SUB>6</SUB>H<SUB>5</SUB>OCH<SUB>2</SUB>CH<SUB>2</SUB>-, C<SUB>6</SUB>H<SUB>5</SUB>CH<SUB>2</SUB>-, CH<SUB>3</SUB>(CH<SUB>2</SUB>)<SUB>3</SUB>OCH<SUB>2</SUB>CH<SUB>2</SUB>Cl; or any one of the following:
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