| 发明名称 |
Modified kunitz domain polypeptide |
| 摘要 |
A polypeptide comprising the amino acid sequence: Met His Ser Phe Cys Ala Phe Lys Ala Asp Asp Gly Pro Cys Arg Ala Ala His Pro Arg Trp Phe Phe Asn Ile Phe Thr Arg Gln Cys Glu Glu Phe Ile Tyr Gly Gly Cys Glu Gly Asn Gln Asn Arg Phe Glu Ser Leu Glu Glu Cys Lys Lys Met Cys Thr Arg Asp (amino acids 3-60 of SEQ ID NO:2), wherein the polypeptide inhibits kallikrein. |
| 申请公布号 |
EP1941867(A1) |
申请公布日期 |
2008.07.09 |
| 申请号 |
EP20070023364 |
申请日期 |
2003.06.06 |
| 申请人 |
DYAX CORPORATION |
发明人 |
LADNER, ROBERT. C.;LEY, ARTHUR, C. |
| 分类号 |
A61K38/57;C12N15/09;A61B;A61K9/00;A61K38/17;A61K38/54;A61K38/55;A61P7/00;A61P9/10;A61P29/00;A61P41/00;A61P43/00;C07K14/47;C12N9/64;C12N9/99;C12N15/15 |
主分类号 |
A61K38/57 |
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