发明名称 |
PREVENTION AND TREATMENT OF COLORECTAL CANCER BY 6-FLUOROURSODEOXYCHOLIC ACID (6-FUDCA) |
摘要 |
Methods for the prevention and treatment of colorectal cancer are provided. Specifically, the method relates to the administration of an effective adenoma or microadenoma preventing amount of 6-fluoroursodeoxycholic acid (6-FUDCA) or a pharmaceutically acceptable salt or pharmaceutically acceptable conjugate thereof to a mammal in need of such treatment. The methods find general use in the prevention of the formation of secondary bile acids, the reduction of deoxycholic acid, and the protection against cytotoxic effects of other bioacids and carcinogens.
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申请公布号 |
CA2253593(C) |
申请公布日期 |
2008.07.08 |
申请号 |
CA19972253593 |
申请日期 |
1997.05.22 |
申请人 |
NOVARTIS AG |
发明人 |
CAPUANO, LEONARD ROBERT;GIBSON, JOYCE COREY |
分类号 |
A61K31/575;A61K31/00;A61P35/00 |
主分类号 |
A61K31/575 |
代理机构 |
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地址 |
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