Azabenzimidazolbaserte forbindelser, fremgangsmater for fremstilling av forbindelsene, anvendelse av forbindelsene samt farmasoytiske sammensetninger inneholdende forbindelsene

摘要

The present invention is directed in part towards methods of modulating the function of serine/threonine protein kinases with azabenzimidazole-based compounds. The methods incorporate cells that express a serine/threonine protein kinase, such as RAF. In addition, the invention describes methods of preventing and treating serine/threonine protein kinase-related abnormal conditions in organisms with a compound identified by the invention. Furthermore, the invention pertains to azabenzimidazole compounds and pharmaceutical compositions comprising these compounds.