发明名称 FUSED HETEROCYCLIC DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND MEDICINAL USE THEREOF
摘要 A compound useful as a preventive or therapeutic agent for sexual-hormone-dependent diseases, etc. It is a fused heterocyclic derivative represented by the following general formula (I). In the formula (I), ring A is a five-membered cyclic unsaturated hydrocarbon or five-membered heteroaryl; RA is halogeno, alkyl, alkenyl, alkynyl, carboxy, alkoxy, carbamoyl, alkylcarbamoyl, etc.; ring B is aryl or heteroaryl; RB is halogeno, alkyl, carboxy, alkoxy, carbamoyl, alkylcarbamoyl, etc.; E1 and E2 each is oxygen, etc.; U is a single bond or alkylene; and X is, e.g., a group represented by Y,-SO2-Y,-O-(alkylene)-Y-, or-O-Z (wherein Y is Z, amino, etc. and Z is cycloalkyl, heterocycloalkyl, aryl, heteroaryl, etc.).
申请公布号 KR20080063827(A) 申请公布日期 2008.07.07
申请号 KR20087010997 申请日期 2006.10.17
申请人 KISSEI PHARMACEUTICAL CO., LTD. 发明人 OHNO KOHSUKE;MIYAGI TAKASHI;OZAWA TOMONAGA;FUSHIMI NOBUHIKO
分类号 C07D487/04;A61K31/519;A61K31/55;A61P13/08 主分类号 C07D487/04
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