发明名称 The use of a BCMA polypeptides and antibodies for the preparation of a pharmaceutical composition for treating a tumour cell that expresses APRIL
摘要 The invention relates to the use of a polypeptide comprising an amino acid sequence that is at least 80 % identical to the sequence set forth from amino acid 1 to 184, or from 1 to 52 of SEQ ID NO: 8 and is capable of binding to APRIL, to a polypeptide comprising amino acid sequence set forth from amino acid 8 to 41 of SEQ ID NO: 8, or an antibody directed against SEQ ID NO: 8 for the preparation of a pharmaceutical composition for treating a tumour cell that expresses A Proliferation Inducing Ligand (APRIL).
申请公布号 SK286331(B6) 申请公布日期 2008.07.07
申请号 SK20020000451 申请日期 2000.10.05
申请人 BIOGEN IDEC MA INC.;APOTECH R & D, S. A. 发明人 SCHNEIDER PASCAL;THOMPSON JEFFREY;CACHERO TERESA;AMBROSE CHRISTINE;RENNERT PAUL
分类号 C12N15/09;A61K;A61K38/00;A61K38/17;A61K39/395;A61P35/00;C07K14/705;C07K14/715;C07K16/28;C07K19/00 主分类号 C12N15/09
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