A NOVEL PROTEIN KINASE C THERAPY FOR THE TREATMENT OF ACUTE LUNG INJURY
摘要
<p>The present invention provides an aerosol formulation of a dPKC inhibitor. The dPKC inhibitor can be, for example, a peptide. The present invention also discloses a method of preventing acute pulmonary cell injury associated with trauma, ALI or ARDS and a method of inhibiting an inflammatory response in pulmonary cells by inhibiting the activity of dPKC. The invention also provides a method of treating a pulmonary disease with an aerosol formulation of a dPKC inhibitor to inhibit neutrophil activity.</p>
申请公布号
WO2008080153(A2)
申请公布日期
2008.07.03
申请号
WO2007US88754
申请日期
2007.12.22
申请人
THE CHILDREN'S HOSPITAL OF PHILADELPHIA;KILPATRICK, LAURIE, ELLEN;KORCHAK, HELEN, MARIE;DEUTSCHMAN, CLIFFORD, S.
发明人
KILPATRICK, LAURIE, ELLEN;KORCHAK, HELEN, MARIE;DEUTSCHMAN, CLIFFORD, S.