| 摘要 |
Coatings are provided in which surfaces may be activated by covalently bo nding a combination ofsilane derivatives (A) to the metal surface, covalentl y bonding a lactone polymer (B) to the silane derivative by in situ ring ope ning polymerization, and depositing at least one layer of a polyester (C) on the bonded lactone polymer. Biologically active agents or therapeutic compo unds may be deposited with any of the polyester layers. Such coated surfaces may be useful in medical devices, in particular stents. |
