Ceramide derivatives, method for preparing the same, and therapeutic agent for treating atopic dermatitis comprising the ceramide derivatives

摘要

Disclosed are ceramide derivatives represented by the following formula 1 or 2, a method for preparing the same, and a therapeutic agent for treating atopic dermatitis including the ceramide derivatives as active ingredients: wherein, R₁ and R₂ are each independently straight or branched alkyl groups having 4 to 22 carbon atoms. The therapeutic agent for treating atopic dermatitis including the ceramide derivatives as active ingredients according to the present invention may be useful to treat atopic dermatitis, or treat other skin diseases that are required for improving skin inflammations or suppressing epidermal proliferation, by suppressing or improving inflammatory conditions in the atopic dermatitis in addition to giving immunoregulatory functions, and suppressing or improving skin disorders, for example epidermal proliferation that is generally observed in the atopic dermatitis.