发明名称 HETEROARYL-HETEROARYL COMPOUNDS AS CDK INHIBITORS FOR THE TREATMENT OF CANCER, INFLAMMATION AND VIRAL INFECTIONS
摘要 The present application describes organic compounds of formula (I), where in m is 0 or 1; n is 0 or 1; A1, A2, A3 and A4 are each, independently, C, C (H) or N; that are useful for the treatment and therapies for protein kinase -associated disorders. They are in particular useful in the treatment or pre vention on amelioration of one or more symptoms of cancer, inflammation, car diac hypertrophy, and HIV by modulating the activity of protein kinases, suc h as CDK1, CDK2, CDK3, CDK4, CDK5, CDK6, CDK7, CDK8 and CDK9, and combinatio ns thereof.
申请公布号 CA2672518(A1) 申请公布日期 2008.07.03
申请号 CA20072672518 申请日期 2007.12.20
申请人 NOVARTIS AG 发明人 TALLARICO, JOHN ANTHONY;HARRINGTON, EDMUND;HINRICHS, JURGEN HANS-HERMANN;CURTIS, DANIEL TIM;BECKWITH, ROHAN ERIC JOHN
分类号 C07D401/04;A61K31/4375;A61K31/444;A61K31/501;A61K31/506;A61K31/53;A61P29/00;A61P31/12;A61P35/00;C07D401/14;C07D403/04;C07D471/04 主分类号 C07D401/04
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