| 摘要 |
<p>A method of treating tumors is provided. More specifically, a method of treating tumors by increasing the exposure of a tumor to a liposome-entrapped agent comprising the step of modulating the composition of cells in a subject's reticuloendothelial system (RES) is described. In addition, a method of treating tumors by increasing the release of drug from a liposome in a tumor comprising the step of modulating the composition of cells in a subject's RES is described. Further, a method of treating tumors by increasing the sensitivity of a tumor to treatment with a liposome-entrapped agent comprising the step of modulating the composition of cells in a subject's RES is described. Still further, a method of treating tumors by individualizing treatment of a tumor comprising the steps of (1) evaluating the composition of RES cells in the tumor, and (2) determining a treatment regimen based on said evaluating, wherein said treatment regimen comprises administering at least one liposome-entrapped agent is described.</p> |
