| 发明名称 |
SUBSTITUTED TETRACYCLINE COMPOUNDS |
| 摘要 |
The present invention pertains, at least in part, to a substituted tetrac ycline compound of Formula (I): wherein X is CHC(R13VY), CR6 R6, C=CR6 R6, S , NR6, or O; E is NR7dR7.beta., OR7f or (CH2)o.iC(=W)WR7s; W is O, S, NR711 or CR75R7*; W is O, S or NR7*; These tetracycline compounds can be used to t reat numerous tetracycline compound-responsive states, such as bacterial inf ections and neoplasms. |
| 申请公布号 |
CA2673466(A1) |
申请公布日期 |
2008.07.03 |
| 申请号 |
CA20072673466 |
申请日期 |
2007.12.21 |
| 申请人 |
PARATEK PHARMACEUTICALS, INC. |
发明人 |
BERNIAC, JOEL;BHATIA, BEENA;ASSEFA, HAREGEWEIN;BOWSER, TODD;VERMA, ATUL;HONEYMAN, LAURA;NELSON, MARK;KIM, OAK K.;ISMAIL, MOHAMED;GRIER, MARK;PAN, JINGWEN;ABATO, PAUL |
| 分类号 |
C07D207/50;A61K31/65;A61P31/04;A61P33/06;C07C237/26;C07D231/12;C07D239/20;C07D241/12;C07D261/02;C07D261/04;C07D263/32;C07D265/02 |
主分类号 |
C07D207/50 |
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