摘要 |
The present invention relates to new AGC kinase inhibitors, in particular to compounds of Formula (I) or (II) or a stereoisomer, tautomer, racemic, metabolite, pro- or predrug, salt, hydrate, or solvate thereof, wherein R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>4</SUP>, R<SUP>5</SUP>, R<SUP>7</SUP>, R<SUP>8</SUP>, q s, L, and Y have the meaning defined in the claims. In particular, the present invention relates to ROCK inhibitors, compositions, in particular pharmaceuticals, comprising such inhibitors, and to uses of such inhibitors in the treatment and prophylaxis of disease. |
申请人 |
DEVGEN N.V.;DEFERT, OLIVIER;LEYSEN, DIRK;VAN ROMPAEY, PHILIPPE |
发明人 |
DEFERT, OLIVIER;LEYSEN, DIRK;VAN ROMPAEY, PHILIPPE |