发明名称 |
Fertility Enhancement Using Lipid Carriers and Bioactive Molecules |
摘要 |
The invention relates to a composition and method for enhancing fertilization. Fertilization enhancement is achieved by effectively delivering bioactive molecules with a lipid anchor (GPI-linked proteins) to the surface of epididymal or ejaculated sperm. The process may be facilitated or promoted in the presence of Clusterin/ApoJ, a well-known lipid carrier. The acquisition of these molecules, such as Sperm Adhesion Molecule 1 (SPAM1) can significantly impact sperm maturation and function. |
申请公布号 |
US2008160003(A1) |
申请公布日期 |
2008.07.03 |
申请号 |
US20070928962 |
申请日期 |
2007.10.30 |
申请人 |
UNIVERSITY OF DELAWARE |
发明人 |
DELEON PATRICIA A.;GRIFFITHS GENEVIEVE S. |
分类号 |
A61K38/43;A01N1/02;A61K35/54 |
主分类号 |
A61K38/43 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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