IN SITU PREPARATION OF SUBSTRATES WITH DI SPERSED GOLD NANOPARTICLES

摘要

The present invention relates to a process for in situ preparation of a substrate with dispersed gold nanoparticles, which comprises the steps of: (a) immersing the substrate in a polycationic polymer solution to form a polycationic thin film on the substrate; (b) immersing the substrate in a polyanionic polymer solution to form a polymeric thin film of the polycationic polymer and the polyanionic polymer; (c) immersing the substrate with the polymeric thin film formed in a solution of a reducible-gold compound; and (d) reducing the reducible-gold compound to disperse gold nanoparticles in the polymeric thin film, whereby the substrate with dispersed gold nanoparticles is prepared. In addition, the present invention relates to a substrate and a biochip comprising it.