发明名称 |
DIFFERENTIATION OF PLURIPOTENT CELLS INTO PRIMARY GERM LAYER PROGENITORS |
摘要 |
This invention relates to the culture of pluripotent cells in a fully humanised chemically defined medium. Cells may be cultured over a prolonged period of time without losing their pluripotent status or may be controllably induced to differentiate into progenitor cells of the three primary germ layers by the addition of differentiation factors, for example differentiation factors which modulate one or more of the Activin/Nodal, FGF, Wnt or BMP signalling pathways. |
申请公布号 |
WO2008056166(A3) |
申请公布日期 |
2008.07.03 |
申请号 |
WO2007GB04291 |
申请日期 |
2007.11.09 |
申请人 |
CAMBRIDGE ENTERPRISE LIMITED;PEDERSEN, ROGER;VALLIER, LUDOVIC |
发明人 |
PEDERSEN, ROGER;VALLIER, LUDOVIC |
分类号 |
C12N5/0735;C12N5/0797 |
主分类号 |
C12N5/0735 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|