TAQMAN MGB PROBE FOR DETECTING MATERNAL INHERITED MITOCHONDRIAL GENETIC DEAFNESS C1494T MUTATION AND ITS USAGE

摘要

A real-time quantitative MGB probe for detecting C1494T mutation in maternal inherited mitochondrial deafness gene and its usage are disclosed. Taqman mutant and wild-type MGB probes and a pair of primers are designed. Genetype of C1494T mutation in maternal inherited mitochondrial deafness gene is analyzed through real-time quantitative Taqman MGB probe method. Therefore maternal inherited mitochondrial deafness can be diagnosed.