发明名称 |
PYRIDAZINONES AND FURAN-CONTAINING COMPOUNDS |
摘要 |
The present invention is directed to pyridazinone compounds of formula (I ) and furan compounds of formula (II), pharmaceutical compositions of compou nds of formula (I) and (II), kits containing these compounds, methods of syn theses, and a method of treatment of a proliferative disease in a subject by administration of a therapeutically effective amount of a compound of formu lae (I) or (II). Both classes of compounds were identified through screening of a collection of small molecule libraries. |
申请公布号 |
CA2673299(A1) |
申请公布日期 |
2008.07.03 |
申请号 |
CA20072673299 |
申请日期 |
2007.12.21 |
申请人 |
SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH |
发明人 |
CHUCHOLOWSKI, ALEXANDER;THIRUVAZHI, MOHAN SANTHANAM;VARMUS, HAROLD E.;DJABALLAH, HAKIM;SOMWAR, ROMEL;SHUM, DAVID |
分类号 |
C07D237/14;A61K31/50;A61K31/501;A61K31/5025;A61P35/00;C07D237/22;C07D401/04;C07D403/04;C07D403/12;C07D405/04;C07D405/12;C07D405/14;C07D409/14;C07D471/04;C07D495/04 |
主分类号 |
C07D237/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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