发明名称 PYRIDAZINONES AND FURAN-CONTAINING COMPOUNDS
摘要 The present invention is directed to pyridazinone compounds of formula (I ) and furan compounds of formula (II), pharmaceutical compositions of compou nds of formula (I) and (II), kits containing these compounds, methods of syn theses, and a method of treatment of a proliferative disease in a subject by administration of a therapeutically effective amount of a compound of formu lae (I) or (II). Both classes of compounds were identified through screening of a collection of small molecule libraries.
申请公布号 CA2673299(A1) 申请公布日期 2008.07.03
申请号 CA20072673299 申请日期 2007.12.21
申请人 SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH 发明人 CHUCHOLOWSKI, ALEXANDER;THIRUVAZHI, MOHAN SANTHANAM;VARMUS, HAROLD E.;DJABALLAH, HAKIM;SOMWAR, ROMEL;SHUM, DAVID
分类号 C07D237/14;A61K31/50;A61K31/501;A61K31/5025;A61P35/00;C07D237/22;C07D401/04;C07D403/04;C07D403/12;C07D405/04;C07D405/12;C07D405/14;C07D409/14;C07D471/04;C07D495/04 主分类号 C07D237/14
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