发明名称 |
Heterobicyclic metalloprotease inhibitors |
摘要 |
The present invention relates generally to amide group containing pharmaceutical agents, and in particular, to amide containing heterobicyclic metalloprotease inhibitor compounds. More particularly, the present invention provides a new class of heterobicyclic MMP-13 inhibiting and MMP-3 inhibiting compounds, that exhibit an increased potency in relation to currently known MMP-13 and MMP-3 inhibitors.
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申请公布号 |
US2008161300(A1) |
申请公布日期 |
2008.07.03 |
申请号 |
US20070001041 |
申请日期 |
2007.12.07 |
申请人 |
ALANTOS PHARMACEUTICALS HOLDING, INC. |
发明人 |
STEENECK CHRISTOPH;GEGE CHRISTIAN;RICHTER FRANK;KROTH HEIKO;HOCHGURTEL MATTHIAS;ESSERS MICHAEL;VAN VELDHUIZEN JOSHUA;NOLTE BERT;GALLAGHER BRIAN M.JR.;FEUERSTEIN TIM;SCHNEIDER MATTHIAS;ARNDT TORSTEN;DENG HONGBO;BEISINGER RALF;WU XINYUAN;BLUHM HARALD;SUCHOLEIKI IRVING;TAVERAS ARTHUR G. |
分类号 |
A61K31/536;A61K31/519;C07D265/36;C07D487/04 |
主分类号 |
A61K31/536 |
代理机构 |
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