发明名称 |
ALFUZOSIN FORMULATIONS, METHODS OF MAKING, AND METHODS OF USE |
摘要 |
Alfuzosin compositions comprising alfuzosin and a release-retarding matrix comprising about 40 to about 80% (by weight) hydroxypropyl methyl cellulose with a maximum apparent viscosity of about 5600 cP, wherein the compositions are bioequivalent to the reference dosage form of NDA #021287 are disclosed. Alfuzosin compositions comprising alfuzosin and a release-retarding matrix comprising about 40 to about 80% (by weight) hydroxypropyl methyl cellulose (HPMC) with a maximum apparent viscosity of about 5600 cP, wherein the dissolution profile of the compositions are substantially identical to the dissolution profile of the reference dosage form of NDA #021287 are also disclosed. Methods of making and using the alfuzosin compositions are also disclosed.
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申请公布号 |
US2008160081(A1) |
申请公布日期 |
2008.07.03 |
申请号 |
US20070953181 |
申请日期 |
2007.12.10 |
申请人 |
MUTUAL PHARMACEUTICAL COMPANY, INC. |
发明人 |
NARINGREKAR GANDHA V.;ARNOLD KRISTIN;DU JIE |
分类号 |
A61K9/22;A61K9/10;A61K31/517;A61P43/00 |
主分类号 |
A61K9/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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