SUBSTRATE FOR OLIGOMER PROBE ARRAY, OLIGOMER PROBE ARRAY AND THE METHOD OF FABRICATING THE SAME

摘要

A substrate for an oligomer probe array and an oligomer probe array are provided to improve integrity and reaction yield of the oligomer probe array, function as a linker or a spacer through an intermediate film included therein to provide a selective reaction region and show less tangling phenomenon and improved resolution of the intermediate film. A substrate for an oligomer probe array comprises: a substrate; and an intermediate film formed on the substrate and represented by a formula(1) and is prepared by providing the substrate and then forming the intermediate film on the substrate. An oligomer probe array comprises: an oligomer probe; a substrate including an active region where the oligomer probe is coupled and an in-active region where the oligomer probe is not coupled; and an intermediate film including a chemical structure represented by a formula(2) on the active region and including the chemical structure of the formula(1) on the inactive region and is prepared by providing the substrate, forming the intermediate film including the structure of the formula(1) on the substrate, exposing at least a portion of the intermediate film to light, and coupling the oligomer probe to at least a portion of the exposed intermediate film. In the formulae, R1 is C2-8 alkyl, aryl, cycloalkyl or cycloalkenyl; R2 is C2-8 alkyl, aryl, cycloalkyl or cycloalkenyl; Y is coupled to a linker, a spacer or the oligomer probe; X is coupled to the substrate directly or via a fixation layer; the fixation layer includes Si(OR)3, wherein R is C1-2 alkyl.