RECEPTOR AGONISTS

摘要

The present invention relates to peptides that are useful as agonists of opioid receptors. In particular, the peptides have a sequence R₁-Paa1-Z-Xaa₁-Haa₁-C₁-C₂-R₂ wherein R₁, R₂, Paa₁, Z, Xaa₁, Haa1, C₁ and C₂ are defined in the specification. Pharmaceutical compositions comprising the peptides and their use in inducing, promoting or otherwise facilitating pain relief and the prophylaxis or treatment of inflammation or conditions that benefit from the alleviation of pain or inflammation are also described.