摘要 |
<p>The invention provides antibodies, including chimeric human antibodies, r ecombinant antibodies, synthetic antibodies, and the nucleic acids encoding them, and methods for making and using these immunoglobulins. The invention provides recombinant and synthetic polypeptide and nucleic acid embodiments of these polypeptides and/or antibodies. The invention also provides polypep tides comprising, or consisting of, consensus human framework regions, or "I ndependently Consensused Frameworks (ICFs)", nucleic acids encoding them, an d libraries and kits comprising these ICFs and/or antibodies of the inventio n, individually and in combinatorial libraries and combinations.</p> |