发明名称 |
Confluence regulated adhesion molecules useful in modulating vascular permeability |
摘要 |
The invention relates to new polypeptide in isolated form belonging to a subfamily of the human Immunoglobulin Superfamily, which polypeptide shows at least 70% sequence homology with the amino acid sequence of the murine Confluency Regulated Adhesion Molecules 1 or 2 (CRAM-1 or CRAM-2) as depicted in FIG. 3 upper and second row, respectively, and antibodies thereto as well as their use in treatment of inflammation and tumors.
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申请公布号 |
US7393651(B2) |
申请公布日期 |
2008.07.01 |
申请号 |
US20040025834 |
申请日期 |
2004.12.30 |
申请人 |
LABORATOIRES SERONO S.A. |
发明人 |
IMHOF BEAT ALBERT;AURRAND-LIONS MICHEL |
分类号 |
G01N33/53;A61P9/00;C07H21/00;C07K2/00;C07K14/00;C07K14/705;C07K16/18;C07K16/28;C12N15/12;C12Q1/68 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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