发明名称 NOVEL SPACER MOIETY FOR POLY(ETHYLENE GLYCOL)- MODIFIED PEPTIDE-BASED COMPOUNDS
摘要 The present invention relates to a compound comprising a peptide moiety, a spacer moiety and a water-soluble polymer moiety such as a poly(ethylene glycol) moiety. The spacer moiety is between the peptide moiety and the water-soluble polymer moiety. The spacer moiety has the structure:-NH-(CH)alpha-[O-(CH)beta]gamma-Odelta-(CH)[epsilon]-Y-wherein alpha, beta, gamma, delta, and [epsilon] are each integers whose values are independently selected.
申请公布号 EA010015(B1) 申请公布日期 2008.06.30
申请号 EA20050001800 申请日期 2004.05.12
申请人 AFFYMAX, INC. 发明人 HOLMES CHRISTOPHER, P.;TUMELTY DAVID;YIN QUN
分类号 A61K47/48;A61K38/00;C07K14/505;C07K14/52 主分类号 A61K47/48
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