摘要 |
The present invention relates to a compound comprising a peptide moiety, a spacer moiety and a water-soluble polymer moiety such as a poly(ethylene glycol) moiety. The spacer moiety is between the peptide moiety and the water-soluble polymer moiety. The spacer moiety has the structure:-NH-(CH)alpha-[O-(CH)beta]gamma-Odelta-(CH)[epsilon]-Y-wherein alpha, beta, gamma, delta, and [epsilon] are each integers whose values are independently selected. |