发明名称 (1-PHENACY-3-PHENYL-3-PIPERIDYLETHYL)PIPERIDINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME
摘要 The invention relates to the compounds of formula: as well as to the salts thereof with inorganic or organic acids, to solvates thereof and/or to hydrates thereof, which have strong affinity and high selectivity for the human NK<SUB>1 </SUB>receptors of substance P. The invention also relates to the process for preparing them, to the intermediate compounds of formula (VII) which are useful for the preparation, to pharmaceutical compositions containing them and to their fuse for the manufacture of medicinal products intended for treating any pathology in which substance P and the human NK<SUB>1 </SUB>receptors are involved.
申请公布号 PL198561(B1) 申请公布日期 2008.06.30
申请号 PL20000350243 申请日期 2000.02.08
申请人 SANOFI-AVENTIS 发明人 DUCOUX JEAN PHILIPPE;EMONDS-ALT XAVIER;GUEULE PATRICK;PROIETTO VICENZO
分类号 C07D401/06;A61K31/445;A61K31/45;A61K31/4545;A61P1/00;A61P1/04;A61P1/08;A61P9/00;A61P11/00;A61P11/08;A61P13/00;A61P13/02;A61P17/00;A61P25/00;A61P25/04;A61P25/06;A61P25/22;A61P25/24;A61P29/00;A61P37/00;A61P43/00;C07D211/00;C07D211/26;C07D211/30;C07D211/34;C07D267/00;C07D295/03;C07D413/06 主分类号 C07D401/06
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