| 摘要 |
An inclusion complex comprising coenzyme Q10 and beta-cyclodextrin, its manner of preparation, and its use in products, such as, for example, pharmaceuticals, cosmetics, and aliments is disclosed. beta-cyclodextrin is dissolved in water at a temperature elevated above room temperature, such as, for example, between 55° C. and water's boiling temperature. While stirring the beta-cyclodextrin-water solution, coenzyme Q10 is added either in a solid form or a solution. Stirring is continued at the evaluated temperature and, then, either at room temperature or a temperature lower than room temperature. The complex enhances the water solubility of the coenzyme Q10 significantly. Also, the complex improves the bioavailability and prophylactic or therapeutical effectiveness of coenzyme Q10. Thus, the inclusion complex solves the problem of poor water-solubility of coenzyme Q10 that renders difficult a manufacture of effective preparations with this enzyme on a non-lipophilic base, as well as its addition to various alimentary, cosmetic, and/or pharmaceutical products. |
