发明名称 DNA SEQUENCE AND PRODUCTION OF GRASS POLLEN ALLERGEN Phi p4 USING RECONBINANT METHODS
摘要 FIELD: genetic engineering. ^ SUBSTANCE: provides genetic sequence of grass pollen main allergen Phi p 4. Fragments of this sequence, combinations of its partial sequences and point mutants have hypoallergenic action. Recombinant molecules of DNA and derivative polypeptides, fragments, new combination of partial sequences and versions can be applied for treatment of diseases associated with grass pollen allergy. ^ EFFECT: proteins produced by recombinant methods can be applied for diagnostics of grass pollen allergosis. ^ 16 cl, 8 dwg, 6 tbl
申请公布号 RU2327739(C2) 申请公布日期 2008.06.27
申请号 RU20050101744 申请日期 2003.06.11
申请人 MERK PATENT GMBKH 发明人 FIBIG KHEL'MUT;NANDI ANDREAS;ZUK ROLAND;KROMUEHLL OLIVER;PETERSEN ARND;BEKKER VOL'F-MAJNKHARD
分类号 C12N15/29;A61K38/00;A61K38/16;A61K39/36;A61K48/00;C07K14/415;C12N15/11;C12N15/63;C12P21/00;G01N33/68 主分类号 C12N15/29
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