发明名称 |
LIPOSOMAL GEL PHTHALOCYANINE PREPARATION FOR PHOTODYNAMIC THERAPY OF TUMORS AND ITS MANUFACTURING |
摘要 |
Liposomal gel hydrophobic phthalocyanine (FCH) preparation for photodynamic therapy of tumors and other diseases is composed of lecithin liposomes or liposomes on the basis of other lipids, with incorporated curing drug, which can be chosen either from a group including hydrophobic hydroxyaluminum phthalocyanine, hydrophobic aluminum phthalocyanine, hydrophobic zinc phthalocyanine, hydrophobic silicone phthalocyanine, or organic silicone phthalocyanine, or hydrophobic phthalocyanine without the core metal; while resulting liposomes are mixed in ratios of 10:1 to 1:10 with a translucent gel, advantageously on the basis of carboxymethylcellulose. The added curing drug can be coated by glucose or other saccharides, by polyethylenglycol or other usable polymers, as lecithin or other lipids, or by sodium chloride or other salts usable in pharmacology. |
申请公布号 |
WO2008074267(A2) |
申请公布日期 |
2008.06.26 |
申请号 |
WO2007CZ00107 |
申请日期 |
2007.11.27 |
申请人 |
INSTITUTE OF PHYSIOLOGY OF AS CR, V.V.I.;RCD, S.R.O.;JEZEK, PETR;NEKVASIL, MILOS;POUCKOVA, PAVLA |
发明人 |
JEZEK, PETR;NEKVASIL, MILOS;POUCKOVA, PAVLA |
分类号 |
A61K9/127;A61K31/409;A61P43/00 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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