发明名称 |
(1R,6S)-2-AZABICYCLO[4.3.0] NONANE-8,8-DIPHOSPHONIC ACID AND ITS USE IN TREATING OR PREVENTING BONE DISORDERS, FOR EXAMPLE, OSTEOPOROSIS OR PAGET'S DISEASE |
摘要 |
<p>Disclosed is a new composition of matter, substantially enantiomerically pure (1R,6S)-2-Azabicyclo-[4.3.0]nonane-8,8-diphosphonic acid, methods of preparing this new composition of matter, a pharmaceutical composition comprising the new composition, and administration of the composition in methods of treating bone disorders such as osteoporosis, osteolytic bone metastasis, rheumatoid arthritis and osteoarthritis.</p> |
申请公布号 |
WO2008076417(A1) |
申请公布日期 |
2008.06.26 |
申请号 |
WO2007US25753 |
申请日期 |
2007.12.14 |
申请人 |
THE PROCTER & GAMBLE COMPANY;UNIVERSITY OF ROCHESTER;EBETINO, FRANK, HALLOCK;BOECKMAN, ROBERT, KENNETH, JR.;SONG, XINYI |
发明人 |
EBETINO, FRANK, HALLOCK;BOECKMAN, ROBERT, KENNETH, JR.;SONG, XINYI |
分类号 |
C07F9/576;A61K31/663;A61K31/675;A61P19/08;A61P19/10 |
主分类号 |
C07F9/576 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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