SUBSTITUTED PIPERIDINES CONTAINING A HETEROARYLAMIDE OR HETEROARYLPHENYL MOIETY

摘要

The invention provides compounds of the formula (I) having PKA and PKB ki nase inhibiting compounds of the formula (I): GP 1 J T 2 J N 4 R N H (I) or salts, solvates, tautomers or N-oxides thereof, wherein (1) GP is a group GP 1: HET 2a a Q G (HNCO)f 7 (R )x N * (GP1) (2) GP is a group GP2: 10 (R )r O 2a a QG (CH2)w N V H N * (GP2) wherein HET is a monocyclic or bicyclic heter ocyclic group containing up to 4 heteroatom ring members; the ring V is a mo nocyclic or bicyclic heteroaryl group of 5 to 10 ring members; and J1, J2, R 4, R7, R10, Q2a, Ga, x, w and f are as defined in the claims