Pharmaceutical Composition Comprising Ppar Regulator

摘要

A pharmaceutical composition containing 1 or more PPAR regulators and 1 or more amino alcohol compounds of the formula (I): wherein R¹ and R², each represents hydrogen or alkyl; R³ represents C1-C6 alkyl or hydroxymethyl; R⁴ represents hydrogen, C1-C6 alkyl, alkoxy or halogen; R⁵ represents substituted phenyl; X represents vinylene (CH-CH), oxygen, sulfur or methylamino; Y represents a single bond, oxygen, sulfur or carbonyl; Z represents a single bond or C1-C8 alkylene; n represents 2 or 3; or pharmacologically acceptable salts thereof. The pharmaceutical composition is used to suppress rejection of organ transplants or skin grafts and to prevent or treat autoimmune diseases.