PHARMACEUTICAL-GRADE BOTANICAL DRUG COMPOSITIONS AND METHODS FOR MANUFACTURING SAME

摘要

A method for producing a pharmaceutical-grade botanical drug composition comprising a selected set of blended-together active ingredients sourced from multiple batches of plant extracts, wherein each active ingredient is provided within a specified concentration range. The first step comprises analyzing each batch from a set of batches of botanical extracts to produce a related data set that identifies and quantifies the active ingredient composition of the batch. The second step comprises mathematically processing, analyzing, computing and optimizing the sets of data generated in the first step, to produce a formula for combining sub-samples from the set of batches of botanical extracts to provide a pharmaceutical-grade botanical drug composition comprising a selected set of active ingredients wherein each ingredient is provided within a specified target concentration range. The third step comprises blending together sub-samples from selected batches of the botanical extracts to produce the pharmaceutical-grade botanical drug composition.