摘要 |
A heart valve prosthesis 4 for human implantation fabricated from bovine pericardial material which is harvested from a region of incipient low calcium content or other material, wherein pre-forming and fixing of the leaflets 5 of the valve to create a rapid change in direction of the surface modifies the stresses within the material leading to a reduction of the peak tensile stress magnitude and concomitant in-use calcification thereby to increase longevity of the valve,
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