METHOD AND COMPOSITIONS FOR INHIBITING MAGE PROTEIN INTERACTION WITH KAP-1
摘要
Method for inhibiting tumor cell formation or tumor cell growth, and method for inducing apoptosis in sperms, the method comprising administering to a patient in need thereof an antagonist that inhibits the binding of MAGE protein to KAP-1, thereby inhibiting MAGE gene function. Also disclosed are pharmaceutical compositions comprising the same, and method for screening a substance that inhibits MAGE protein binding to KAP-1.
申请公布号
WO2008076857(A2)
申请公布日期
2008.06.26
申请号
WO2007US87515
申请日期
2007.12.14
申请人
WISCONSIN ALUMNI RESEARCH FOUNDATION;LONGLEY, BRUCE JACK;YANG, BING;WU, JIANQIANG;MA, YONGSHENG
发明人
LONGLEY, BRUCE JACK;YANG, BING;WU, JIANQIANG;MA, YONGSHENG