发明名称 |
THERAPEUTIC COMPOSITION FOR INTERSTITIAL PHEUMONIA |
摘要 |
Disclosed is a therapeutic agent for interstitial pneumonia, which ensure s to exert the effect of superoxide dismutase (SOD) contained therein. Speci fically disclosed is a therapeutic agent for interstitial pneumonia, which c omprises 10 to 100 mg of lecithin-conjugated superoxide dismutase represente d by the general formula (I), which further comprises sucrose for the purpos e of increasing its stability, and which has a dosage form suitable for intr avenous administration. SOD'(Q-B)m (I) wherein SOD' represents a residue of superoxide dismutase; Q represents a chemical crosslink; B represents a resi due produced by removing a hydrogen atom from a hydroxy group in lysolecithi n which has the hydroxy group at position-2 of a glycerol moiety therein; an d m represents an average number of lysolecithin molecules bound to one supe roxide dismutase molecule and is an integer of 1 or greater.
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申请公布号 |
CA2671668(A1) |
申请公布日期 |
2008.06.26 |
申请号 |
CA20072671668 |
申请日期 |
2007.12.19 |
申请人 |
LTT BIO-PHARMA CO., LTD. |
发明人 |
MIZUSHIMA, YUTAKA;MURAKAMI, MASAHIRO;KURODA, TOSHIHISA;FUKUZAKI, TOMOHARU;SHIRAI, KOUJI;KAWASHIMA, TATSUO |
分类号 |
A61K38/45;A61K9/08;A61K31/573;A61K45/00;A61K47/24;A61K47/48;A61P11/00;A61P29/00 |
主分类号 |
A61K38/45 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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