发明名称 |
6-AMINOIMIDAZO[1,2-b]PYRIDAZINE ANALOGS AS RHO KINASE INHIBITORS FOR THE TREATMENT OF RHO KINASE-MEDIATED DISEASES AND CONDITIONS |
摘要 |
Methods for using 6-aminoimidazo[1,2-b]pyridazine analogs are disclosed herein to treat rho kinase-mediated diseases or rho kinase-mediated conditions, including controlling intraocular pressure and treating glaucoma, are disclosed. Ophthalmic pharmaceutical compositions useful in the treatment of eye diseases such as glaucoma, and additionally useful for controlling intraocular pressure, the compositions comprising an effective amount of 6-aminoimidazo[1,2-b]pyridazine analogs, are disclosed herein.
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申请公布号 |
US2008153813(A1) |
申请公布日期 |
2008.06.26 |
申请号 |
US20070960476 |
申请日期 |
2007.12.19 |
申请人 |
ALCON MANUFACTURING, LTD. |
发明人 |
CHEN HWANG-HSING;RUSINKO ANDREW;HELLBERG MARK R.;SEVERNS BRYON S.;HENDERSON ALAN J.;GUO CHENG;HADDEN MARK |
分类号 |
A61K31/5025;A61K31/5377;A61K31/5513;A61P27/02 |
主分类号 |
A61K31/5025 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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