摘要 |
<p>The present invention relates to an LK8-Fc fusion protein, which has increased angiogenesis inhibitory activity and in vivo stability. More specifically, relates to an LK8-Fc fusion protein in which an LK8 protein having angiogenesis inhibitory activity is fused with the Fc region of human immunoglobulin IgGl, as well as a composition for treating cancer, which contains the fusion protein. The LK8-Fc fusion protein has not only angiogenesis inhibitory activity leading to anticancer and metastasis inhibitory activitivies, but also a very long in vivo half-life, and thus can be used as a more efficient and economic cancer therapeutic agent or cancer inhibitor.</p> |
申请人 |
MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE;YU, HYUN-KYUNG;YOON, YEUP;AHN, JIN-HYUNG;LIM, IN-HWAN;LEE, HO-JEONG;KIM, JANG-SEONG;PARK, DOO-HONG |
发明人 |
YU, HYUN-KYUNG;YOON, YEUP;AHN, JIN-HYUNG;LIM, IN-HWAN;LEE, HO-JEONG;KIM, JANG-SEONG;PARK, DOO-HONG |