发明名称 PROCESS FOR THE PREPARATION OF SILDENAFIL
摘要 <p>The present invention is directed to a process for the preparation of the compound of Formula (I) : comprising the step of converting a compound selected from the group consisting of the compounds of formulae (II), (III) and (IV) : wherein X is halogen, in one or more steps to give the compound of formula (I). The invention is also directed to a process for the preparation of a pharmaceutical composition comprising the compound of formula (I) or a pharmaceutically acceptable salt or solvate thereof. Moreover, the invention relates to intermediates suitable for use in the above processes as well as processes for their preparation.</p>
申请公布号 WO2008074512(A1) 申请公布日期 2008.06.26
申请号 WO2007EP11355 申请日期 2007.12.21
申请人 KRKA, TOVARNA ZDRAVIL, D.D., NOVO MESTO 发明人 TIAN, GUANGHUI;ZHU, YI;LIU, ZHENG;WANG, ZHEN;SHEN, JINGSHAM;BOMBEK, SERGEJA;STROPNIK, TADEJ
分类号 C07D487/04 主分类号 C07D487/04
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